Thienopyridine derivatives
Web22 May 2024 · These antithrombotic agents include antiplatelet agents, such as aspirin and thienopyridine derivatives, and anticoagulants, such as warfarin, dabigatran, and heparin. The guideline categorizes endoscopic procedures into four categories—conventional endoscopy, endoscopic biopsy, low bleeding risk gastrointestinal endoscopy, and high … WebThe present invention provides thienopyridine derivatives, which are useful as anti-inflammatory drugs, particularly as remedies for arthritis; processes for producing them, and pharmaceutical compositions containing them. The thienopyridine derivatives are represented by the formula (I), wherein G is a halogen atom, hydroxyl group, an optionally …
Thienopyridine derivatives
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WebThis patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results. Web26 Oct 2024 · A series of thienotetrahydropyridine derivatives, in which the 2-position in the thiophene ring was blocked by substitution, for example, with an amino, carboxamido, ureido, or thioureido function, were …
WebThe carboxarnide derivatives (X-XII) interacted with CS 2 giving pyridothienopyrirnidines (XX-XXII), while interaction with nitrous acid, pyridothienotriazines (XXIII-XXV) were produced. Key Words: Synthesis thienopyridine pyridothienopyrimidine pyridothienotriazine Web11 Jun 2024 · A group of diversified thienopyridine derivatives exhibited a wide range of biological activity was used to investigate its structural requirements by using DFT and 3D-Quantitative structure activity relationship. Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were established using ...
Web15 Jan 2015 · Among antithrombotic drugs, thienopyridine derivatives, in particular, have a strong tendency to cause bleeding after gastric ESD, and in many cases, postoperative bleeding occurred after ...
Web11 Sep 2007 · The high pharmacological potential of thienopyridine derivatives stimulates the elaboration of new ingenious methods, nonconventional approaches, and regio- and stereoselective procedures that ...
Web25 Apr 2024 · To develop of an effective synthetic methodology for biologically relevant thienopyridines, a concise and efficient protocol is described for the synthesis of a series of substituted thienopyridine and thienoquinoline derivatives with high selectivity using EtOCS2K as the sulfur source. The reaction proceeds via metal-free, site-selective C–H ... floa bank fonctionnementWebThe present invention relates to thienopyridine derivatives. More particularly, this invention is directed to thienopyridine derivatives which have been found to be particularly available as an antiulcer agent, to their preparation, to their use, and to pharmaceutical formulations containing the compounds. great harvest in ann arbor michWebThe thienopyridine class of antiplatelet agents has been developed to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. They are prescribed in patients who either do not tolerate aspirin or … great harvest in neenahWeb1 Nov 2010 · Novel thienopyridine derivatives 1b–1r were synthesized, based on a hit compound 1a that was found in a previous cell-based screening of anticancer drugs. Compounds 1a – 1r have the following features: (1) their anticancer activity in vitro was first reported by our group. great harvest in chico caWebAs part of our continuous efforts in the synthesis of new thienopyridine derivatives containing biphenyl system, we arrived at the synthesis of 4 0 -(6,7-dihydro-4H-thieno [3,2c]pyridin-5-ylmethyl ... great harvest in boiseWebThe present thienopyrimidine derivatives of formula (I) and compositions having ganodotropin-releasing hormone antagonistic activity are useful as propylactics or therapeutic agents for the prevention or treatment of several hormone dependent diseases, for example, a sex hormone dependent cancer (e.g., prostatic cancer, uterine cervical … great harvest in lake charles laWeb30 Nov 2024 · The scientists studied the reactions of thienopyridine derivatives with substances from six different groups: alkynes, aldehydes, alcohols, and other organic compounds. great harvest indianapolis